2 Results for "

PD166285

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PD166285" in MCE Product Catalog:

Cat. No.: HY-175819
CAS No.: 717094-37-6
Target:  

Wee1 Apoptosis

Research Areas:  

Cancer

PD-166285 is a PKMYT1 inhibitor, with an IC50 value of 17 nM. PD166285 shows strong antiproliferative effects against CCNE1-amplified OVCAR3 cells (IC50 = 0.14 μM) and HCC1569 cells (IC50 = 0.21 μM). PD166285 induces apoptosis and arrests CCNE1-amplified HCC1569 cells at the G1/S phase of the cell cycle. PD166285 can be used for the research of PKMYT1-targeted therapies for CCNE1-amplified cancers .
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Cat. No.: HY-132559S
CAS No.: 1246814-59-4
PD-166285-d4 is the deuterium labeled PD-166285 .
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