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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
PLX3618
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "PLX3618" in MCE Product Catalog:
Cat. No.: HY-161779
CAS No.: 2851986-76-8
Research Areas:
PLX-3618 is a selective BRD4 molecular glue degrader with a DC50 of 12.2 nM. PLX-3618 promotes the polyubiquitination and subsequent proteasomal degradation of BRD4 by recruiting the E3 ligase substrate receptor DCAF11. PLX-3618 inhibits the proliferation of various cancer cells and induces apoptosis in acute myeloid leukemia (AML) cells. PLX-3618 can be used in studies related to acute myeloid leukemia (AML) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
