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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PPM3
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PPM3" in MCE Product Catalog:
Cat. No.: HY-149616
CAS No.: 3032388-42-1
PPM-3 is a highly selective ERK5 PROTAC degrader that mediates the degradation of ERK5 protein by recruiting VHL. PPM-3 inhibits ERK5 kinase activity with an IC50 of 62.4 nM. PPM-3-mediated ERK5 degradation exhibits a hook effect. PPM-3 exerts no significant direct inhibitory effect on the proliferation and migration of cancer cells. PPM-3 can be used in studies related to macrophage polarization and tumor immunity .
Cat. No.: HY-184975
CAS No.: 1234481-27-6
Research Areas:
ERK5 ligand-2 is an ERK5 ligand. ERK5 ligand-2 can serve as a ligand for the target protein in the synthesis of PROTAC ERK5 degraders, such as PPM-3 (HY-149616). ERK5 ligand-2 is suitable for use in cancer research .
Cat. No.: HY-P703018
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PHLPP2; PPM3B; Prev. PHLPPL; Protein Phosphatase, Mg2+/Mn2+ Dependent 3B; PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 2; PH Domain And Leucine Rich Repeat Protein Phosphatase-Like; KIAA0931; PHLPP-Like; PH Domain And Leucine Rich Repeat P
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
