ERK5 ligand-2
ERK5 ligand-2 is an ERK5 ligand. ERK5 ligand-2 can serve as a ligand for the target protein in the synthesis of PROTAC ERK5 degraders, such as PPM-3 (HY-149616). ERK5 ligand-2 is suitable for use in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1234481-27-6
- Formula: C24H27N7O2
- Molecular Weight:445.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
ERK5 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.23 μM
Compound: 14
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Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis
Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis
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[PMID: 21412406] |
Chemical Information
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CAS No. 1234481-27-6
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Molecular Weight 445.52
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Formula C24H27N7O2
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SMILES
O=C(C1=CC=CC=C1N(C)C2=NC(NC3=CC=C(C=C3OC)N4CCNCC4)=NC=C25)N5C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ERK5 ligand-2 Related Classifications
HY-184975 Related Classifications
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