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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
PR825
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "PR825" in MCE Product Catalog:
Cat. No.: HY-114438
CAS No.: 935888-08-7
Target:
Research Areas:
PR-825 is a selective constitutive proteasome β5 chymotrypsin-like active site inhibitor with an IC50 value of 17 nM for X/β5. PR-825 reduces MHC-I expression. PR-825 has no effect on collagen antibody-induced arthritis. PR-825 delays the onset and reduces the severity of experimental autoimmune encephalomyelitis in LMP7-deficient mice while inhibiting IFN-γ/IL-17 production, but has no such effect in wild-type mice .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
