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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
PRDM9
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "PRDM9" in MCE Product Catalog:
2
2 Cited Publications
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Research Areas:
MRK-740, a chemical probe, is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80?nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 (IC50?=?0.8?μM) .
Cat. No.: HY-RS11073
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PRDM9 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDM9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25719
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Prdm9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Prdm9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19230
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Prdm9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prdm9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176820
CAS No.: 2421146-31-6
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MRK-740-NC is a PRDM7/9 histone methyltransferase inhibitor. MRK-740-NC is a negative control compound of MRK-740 (HY-114209). MRK-740-NC has no inhibitory activity for PRDM7 and PRDM9 by replacing the methyl pyridine moiety of MRK-740 by a phenyl group .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
