2 Results for "

PX866

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PX866" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N6775
CAS No.: 502632-66-8
Synonyms: PX-866
Target:  

PI3K

연구분야:  

Cancer

Sonolisib (PX-866), an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity .
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Cat. No.: HY-113572
CAS No.: 1012327-63-7
Target:  

PI3K

연구분야:  

Cancer

PX-866-17OH is the metabolite of PX-866 (Sonolisib, HY-N6775) and a pan-isoform inhibitor of PI3K with IC50s of 14, 57, 131, and 148 nM against PI3Kα, PI3Kβ, PI3K , and PI3Kδ, respectively .
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