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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Pemetrexed
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Pemetrexed" in MCE Product Catalog:
40
40 Publications Verification
Synonyms: LY231514
Target:
Research Areas:
Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
40
40 Publications Verification
Synonyms: LY231514 disodium
Target:
Research Areas:
Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
40
40 Publications Verification
Synonyms: LY231514 disodium hemipenta hydrate
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Pemetrexed (LY231514) disodium hemipenta hydrate is a CNS-penetrant antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
40
40 Publications Verification
Synonyms: LY231514 disodium heptahydrate
Target:
Research Areas:
Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Cat. No.: HY-10820R
CAS No.: 137281-23-3
Synonyms: LY231514 (Standard)
Target:
Research Areas:
Pemetrexed (Standard) is the analytical standard of Pemetrexed. This product is intended for research and analytical applications. Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
Cat. No.: HY-137773
CAS No.: 869791-42-4
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N-Methyl pemetrexed is an impurity of Pemetrexed. Pemetrexed is an antifolate cytotoxic agent that can be used for the research of cancer .
Synonyms: Pemetrexed 6-oxo diacid impurity
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Research Areas:
LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820) .
Cat. No.: HY-10820BR
CAS No.: 357166-29-1
Synonyms: LY231514 disodium heptahydrate (Standard)
Target:
Research Areas:
Pemetrexed (disodium heptahydrate) (Standard) is the analytical standard of Pemetrexed (disodium heptahydrate). This product is intended for research and analytical applications. Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Cat. No.: HY-126830
CAS No.: 1286279-90-0
Target:
Research Areas:
Antifolate C2 is an anti-folate compound that has inhibitory effects on the proliferation of non-squamous non-small cell lung cancer (NS-NSCLC). Antifolate C2 achieves tumor selectivity by targeting proton-coupled folate transporter (PCFT), which is more selective to PCFT than the commonly used anti-folate drug Pemetrexed (HY-10820). Antifolate C2 blocks the biosynthesis of deoxypurine nucleotides by inhibiting glycinamide ribonucleotide formyltransferase (GARFTase), ultimately inhibiting the proliferation of tumor cells. Antifolate C2 can be used in studies of NS-NSCLC, especially in patients who do not respond well to Pemetrexed .
Cat. No.: HY-10820S
CAS No.: 1129408-57-6
Synonyms: LY231514-d5
Cat. No.: HY-10820AS
Synonyms: LY231514-d5 disodium
Cat. No.: HY-13781R
CAS No.: 357166-30-4
Synonyms: LY231514 disodium hemipenta hydrate (Standard)
Research Areas:
Pemetrexed (disodium hemipenta hydrate) (Standard) is the analytical standard of Pemetrexed (disodium hemipenta hydrate). This product is intended for research and analytical applications. Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Cat. No.: HY-W769288
Synonyms: LY231514 disodium-13C5
Cat. No.: HY-Z3384
CAS No.: 52454-78-1
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Research Areas:
Pemetrexed impurity 25 is an impurity of Pemetrexed (HY-10820).
Cat. No.: HY-129976
CAS No.: 1851348-04-3
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Research Areas:
Pemetrexed tromethamine dihydrate is a chemotherapy drug used to treat pleural mesothelioma and non-small cell lung cancer, exhibiting potent anti-cancer activity.
Cat. No.: HY-Z3384R
CAS No.: 52454-78-1
Target:
(S)-4-amino-5-ethoxy-5-oxopentanoic acid (Pemetrexed Disodium Impurity） (Standard) is the analytical standard of (S)-4-amino-5-ethoxy-5-oxopentanoic acid (Pemetrexed Disodium Impurity）. This product is intended for research and analytical applications.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
