1 Result for "

Pro-GA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pro-GA" in MCE Product Catalog:

Cat. No.: HY-171030
CAS No.: 2222067-12-9
Research Areas:  

Cancer

Pro-GA is a γ-glutamyl cyclotransferase (GGCT) inhibitor. Pro-GA inhibits the enzymatic activity of GGCT, disrupts glutathione homeostasis, induces the production of mitochondrial ROS, and upregulates the expression of p21, p27 and p16 in cells. Pro-GA inhibits the growth of cancer cells, induces cell cycle arrest and cellular senescence. Pro-GA exerts anti-tumor effects in breast cancer xenograft mouse models. Pro-GA can be used in research related to bladder cancer and breast cancer .
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