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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Protein regulator of cytokinesis 1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Protein regulator of cytokinesis 1" in MCE Product Catalog:
Cat. No.: HY-P74620
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRC1; Anaphase Spindle Elongation 1 Homolog (S. Cerevisiae); Protein regulator of cytokinesis 1; Anaphase Spindle Elongation 1 Homolog; MAP65; Protein Regulating cytokinesis 1; ASE1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-179466
CAS No.: 2551033-16-8
Target:
Research Areas:
BKT300 is a potent and selective protein regulator of cytokinesis 1 (PRC1) inhibitor. BKT300 inhibits PRC1 dephosphorylation at T481, disrupts actin and microtubule formation, induces G2/M cell cycle arrest, triggers mitotic catastrophe, and promotes apoptosis, thereby inhibiting proliferation and migration of acute myeloid leukemia (AML) cells while sparing normal cells. BKT300 inhibits tumor growth in mouse xenograft AML models. BKT300 can be used for the research of AML .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
