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Results for "

Pyochelin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (2) Endogenous Metabolite (1) Fungal (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Aeruginoic acid	Others	Cardiovascular Disease
Aeruginoic acid is a pyochelin biosynthetic byproduct, is an iron chelator. Aeruginoic acid exhibits hypotensivee activity .

*Pyochelin*	Endogenous Metabolite Bacterial	Infection
Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe ³⁺ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn ²⁺, Co ²⁺, and Ni ²⁺, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection .

Dihydroaeruginoic acid (Rac)-CGP 52547	Antibiotic Fungal Bacterial	Infection Cancer
Dihydroaeruginoic acid ((Rac)-CGP 52547), an antifungal antibiotic, is a thiazoline iron chelator. Dihydroaeruginoic acid is the condensation product of salicylate and one cysteine residue. Dihydroaeruginoic acid chelates Fe(III), inhibits DNA replication via ribonucleotide reductase, induces G1/S cell cycle block, reduces leukemia cell clonogenic viability. Dihydroaeruginoic acid inhibits phytopathogenic fungi and bacteria, suppresses Candida albicans development, and inhibits Agrobacterium tumefaciens biofilm formation via extracellular iron sequestration. Dihydroaeruginoic acid can be used for the research of phytopathogenic fungal and bacterial infections, and leukemia .

Aeruginoic acid	Structural Classification Natural Products Microorganisms Source Classification	Others
Aeruginoic acid is a pyochelin biosynthetic byproduct, is an iron chelator. Aeruginoic acid exhibits hypotensivee activity .

*Pyochelin*	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Source Classification	Endogenous Metabolite Bacterial
Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe ³⁺ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn ²⁺, Co ²⁺, and Ni ²⁺, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection .

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