1 Result for "

Quarfloxin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Quarfloxin" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-14776
CAS No.: 865311-47-3
Purity:  99.87%
Synonyms: CX-3543
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template .
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