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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
146 Results for "
RAW264 cells
" in MedChemExpress (MCE) Product Catalog:
Products (146)
146 Results for "RAW264 cells" in MCE Product Catalog:
8
8 Publications Verification
ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .
3
3 Cited Publications
Cat. No.: HY-N0617
CAS No.: 80651-76-9
Category:
Cardiovascular Disease Plants Moraceae Flavanonols Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology Morus alba Linn.
Target:
2
2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
2
2 Cited Publications
Cat. No.: HY-N0569
CAS No.: 18449-41-7
2
1
Category:
Ranunculaceae Coumarins Phenylpropanoids Plants Cimicifuga racemosa (L.) Nutt. Disease Research Fields Inflammation/Immunology
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1
1 Cited Publications
Synonyms: 4-Hydroxy-3-methoxycinnamaldehyde
Category:
other families Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Category:
Bletilla striata (Thunb. ex Murray) Rchb. f. Orchidaceae Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields
Target:
1
1
Category:
Terpenoids Sesquiterpenes Cyperaceae Cyperus rotundus L. Plants Disease Research Fields Inflammation/Immunology
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1
1 Cited Publications
Target:
Research Areas:
T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50=27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice.
1
1 Cited Publications
Cat. No.: HY-N7012
CAS No.: 29080-58-8
Synonyms: 5-Hydroxy-3',4',7-trimethoxyflavone
Cat. No.: HY-155751
Purity: 99.37%
Research Areas:
HMGB1-IN-1 (compound 6) displays strong NO inhibitory effect in RAW264.7 cells with IC50 value of 15.9 ± 0.6 μM. HMGB1-IN-1 inhibit the HMGB1/NF-κB/NLRP3 pathway. HMGB1-IN-1 shows good anti-inflammatory activity and good anti-sepsis effects in kidney injury .
Category:
Quinones Monophenols Anthraquinones Rubiaceae Phenols Plants Damnacanthus major Sieb. et Zucc.
Target:
Cat. No.: HY-W068682
CAS No.: 528-71-2
Synonyms: Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL . 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris .
Cat. No.: HY-171274
CAS No.: 149775-26-8
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Research Areas:
DOCK5-IN-1 (Compound 14) is the inhibitor for DOCK5 and exhibits no toxicity (100 μM) in cell RAW264.7 .
Cat. No.: HY-N8559
CAS No.: 40738-40-7
Target:
Research Areas:
Ethyl gentisate (Ethyl 2,5-dihydroxybenzoate) is a dual modulator for cell differentiation, that enhances the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and alkaline phosphatase activity, inhibits RANKL-activated osteoclastogenesis in RAW264.7 cells, and balances the bone remodeling process .
Cat. No.: HY-N9337
CAS No.: 21233-18-1
Category:
Metabolic Disease Plants Iridoids Terpenoids Gentianaceae Swertia mussotii Franch. Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W753791
CAS No.: 2111-75-3
Target:
Research Areas:
(±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
