256459-34-4
Chemical Structure
Dactylorhin A
- No. CAS: 256459-34-4
- Formula:C40H56O22
- Molecular Weight:888.86
IUPAC Name: bis(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl) (R)-2-isobutyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)succinate
InChIKey: QUCKZYFUROTIBC-HDQVGPIMSA-N
SMILES: O=C(OCC1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C=C1)C[C@@](CC(C)C)(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(OCC4=CC=C(O[C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)C=C4)=O
Biological Activity: Dactylorhin A is a glucoside and succinate derivative ester inhibitor that can be found in Bletilla striata tubers and Gymnadenia conopsea rhizomes, with activity against nitric oxide production in macrophage cells[1][2].Dactylorhin A suppresses lipopolysaccharide-induced nitric oxide generation via a cytotoxicity-independent pathway[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Dactylorhin A | 99.85% | Dactylorhin A is a glucoside and succinate derivative ester inhibitor that can be found in Bletilla striata tubers and Gymnadenia conopsea rhizomes, with activity against nitric oxide production in macrophage cells.Dactylorhin A suppresses lipopolysaccharide-induced nitric oxide generation via a cytotoxicity-independent pathway. | ||||||||||||||||||||
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References
- [1]. Zhao Y, et al. Chemical constituents from Bletilla striata and their NO production suppression in RAW 264.7 macrophage cells. Journal of Asian natural products research. 2018 Apr;20(4):385-390. [Content Brief]
- [2]. Cai M, et al. Chemical fingerprint analysis of rhizomes of Gymnadenia conopsea by HPLC-DAD-MSn. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2006 Dec 05;844(2):301-7. [Content Brief]
