2111-75-3
2111-75-3
Chemical Structure
(±)-Perillaldehyde
- CAS No.: 2111-75-3
- Formula:C10H14O
- Molecular Weight:150.22
IUPAC Name: 4-(prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde
InChIKey: RUMOYJJNUMEFDD-UHFFFAOYSA-N
SMILES: CC(C1CCC(C=O)=CC1)=C
Biological Activity: (±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(±)-Perillaldehyde | 96.70% | (±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM. | ||||||||||||||||||||
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Perillic acid | 99.94% | Perillic acid is the metabolite of Perillyl alcohol (HY-N7000). Perillic acid induces lung cancer cell cycle arrest and apoptosis. Perillic acid shows anti-HSV-1 and immunomodulatory activities. | ||||||||||||||||||||
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(S)-(-)-Perillic acid | 99.9% | (S)-(-)-Perillic acid is a terpenoid plant extract with antimicrobial and anticancer activities. (S)-(-)-Perillic acid induces cell apoptosis and cell cycle arrest, and increases the levell of Bax, Bcl2, p21 and caspase-3 proteins. (S)-(-)-Perillic acid can be used for cancer and infection research. | ||||||||||||||||||||
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(S)-(-)-Perillyl alcohol | 97.0% | (S)-(-)-Perillyl alcohol, a monoterpene, is an orally active farnesyl transferase and geranylgeranyl transferase inhibitor. (S)-(-)-Perillyl alcohol up-regulates the mannose-6-phosphate receptor, facilitating TGF-β1 activation and cytostasis,. (S)-(-)-Perillyl alcohol induces apoptosis in cancer cells, modulates cyclin D1 and AP-1 activity. (S)-(-)-Perillyl alcohol exhibits antitumor activity against sarcoma tumors in mice. (S)-(-)-Perillyl alcohol can be used for the research of squamous cell carcinoma of the esophagus and sarcoma 180. | ||||||||||||||||||||
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Phellandral | Phellandral is an aldehyde compound that can be found in Eucalyptus camaldulensis and Thymus seravschanicus. The phellandral-containing eucalyptus essential oil exhibits significant inhibitory effects on various plant pathogenic fungi, especially on Aspergillus flavus. Phellandral, together with other oxygenated monoterpenoids, constitutes an important basis for the antibacterial activity of the essential oil. | |||||||||||||||||||||
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L-Perillaldehyde | 90.0% | L-Perillaldehyde is a major component in the essential oil containing in Perillae Herba. Inhalation of L-Perillaldehyde shows antidepressant-like activity through the olfactory nervous function. | ||||||||||||||||||||
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Perillyl alcohol (Standard) | ≥98% | Perillyl alcohol (Standard) is the analytical standard of Perillyl alcohol (HY-N7000). Perillyl alcohol is an orally active monoterpene. Perillyl alcohol exhibits multiple activities such as analgesic, anti-inflammatory, anti-tumor, anti-angiogenic, and anti-nociceptive effects. Perillyl alcohol can induce apoptosis and cell cycle arrest in tumor cells. | ||||||||||||||||||||
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(R)-Perillaldehyde | (R)-Perillaldehyde is a natural product. | |||||||||||||||||||||
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(S)-(+)-Carvone | 99.26% | (S)-(+)-Carvone is an orally active natural product. (S)-(+)-Carvone increases the activity of antioxidant enzymes (SOD, CAT) and ROS, reduces the levels of oxidative stress markers (MDA, AChE), reduces the secretion of proinflammatory cytokines (IL-1β, IL-4, IL-6, IL-10), and downregulates NLRP3. (S)-(+)-Carvone increases the activities of caspase-8, -9 and -3. (S)-(+)-Carvone induces apoptotic death. (S)-(+)-Carvone has antimanic-like effect, liver protection and anticancer activity against skin cancer. (S)-(+)-Carvone improves memory and arthritis. | ||||||||||||||||||||
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(-)-Limonene | 98.59% | (-)-Limonene ((S)-(-)-Limonene) is orally active and can cause mild bronchoconstriction. (-)-Limonene alleviates cytosolic and mitochondrial oxidative stress by inhibiting the increase of calcium ions (Ca2+) and Ca2+/calmodulin-dependent protein kinase II (CaMKII). It also exerts anti-stress effects by inhibiting the activity of the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, (-)-Limonene can be used as an antibacterial agent in aquaculture. | ||||||||||||||||||||
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References
- [1]. N Ito, et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. Evid Based Complement Alternat Med. 2011:2011:512697. [Content Brief]
- [2]. Takuya Uemura, et al. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J Agric Food Chem. 2018 Apr 4;66(13):3443-3448. [Content Brief]
