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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
ROMK Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "ROMK Inhibitor" in MCE Product Catalog:
3
3 Cited Publications
Target:
Forschungsgebiete:
VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney .
Target:
Forschungsgebiete:
VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 can be used for neurological research with HY-108585 (the equivalent of VU591 hydrochloride) .
Target:
Forschungsgebiete:
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride) .
Art. -Nr.: HY-132201
CAS. Nr.: 1548286-45-8
Target:
Forschungsgebiete:
MK-8153 is a potent, selective and orally active inhibitor of renal outer medullary potassium channel (ROMK), with IC50s of 5 nM, 34 μM for ROMK electrophysiology (EP) and hERG EP, respectively. MK-8153 can be used as the diuretic/atriuretic .
Art. -Nr.: HY-18277
CAS. Nr.: 1255204-84-2
Target:
Forschungsgebiete:
MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM.
Art. -Nr.: HY-162555
CAS. Nr.: 2254333-97-4
Target:
Forschungsgebiete:
BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research .
Art. -Nr.: HY-123803
CAS. Nr.: 2213468-04-1
Target:
Forschungsgebiete:
PF-06807656 is a selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor. PF-06807656 has an IC50 of 61 nM against hROMK in patch-clamp assays. PF-06807656 exhibits high selectivity for inhibiting rat ROMK and is insensitive to N171D pore mutations. PF-06807656 may be used in cardiovascular disease research .
Art. -Nr.: HY-124687
CAS. Nr.: 1914944-54-9
Target:
Forschungsgebiete:
ROMK-IN-32 is a renal outer medullary potassium channel (ROMK) inhibitor with an IC50 of 35 nM. ROMK-IN-32 also inhibits hERG with an IC50 of 22 μM .
Art. -Nr.: HY-110076
CAS. Nr.: 1783987-83-6
Target:
Forschungsgebiete:
VU590 dihydrochloride is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 dihydrochloride is not a good probe of ROMK function in the kidney .
Art. -Nr.: HY-P1403
Target:
Forschungsgebiete:
Art. -Nr.: HY-168880
CAS. Nr.: 2254335-06-1
Target:
Forschungsgebiete:
ROMK-IN-2 (compond 1) is a potent renal outer medullary potassium (ROMK) inhibitor .
Art. -Nr.: HY-108595R
CAS. Nr.: 313505-85-0
Target:
Forschungsgebiete:
VU590 (Standard) is the analytical standard of VU590 (HY-108595). This product is intended for research and analytical applications. VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the Kidney .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
