4 Results for "

RXFP2

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "RXFP2" in MCE Product Catalog:

Cat. No.: HY-150186
CAS No.: 2971704-85-3
Target:  

RXFP Receptor

Research Areas:  

Metabolic Disease

RXFP2 agonist 2 is a selective, orally active and allosteric RXFP2 agonist with an EC50 value of 0.38 μM. RXFP2 agonist 2 induces osteoblast mineralization. RXFP2 agonist 2 increases bone formation in female mice. RXFP2 agonist 2 has the potential for the research of osteoporosis .
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Cat. No.: HY-150185
CAS No.: 2971704-58-0
Target:  

RXFP Receptor

Research Areas:  

Metabolic Disease

RXFP2 agonist 1 (Compound 1715) is a potent RXFP2 agonist with an EC50 value of 0.06 µM. RXFP2 agonist 1 has the potential for the research of osteoporosis .
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Cat. No.: HY-RS12358
Research Areas:  

Others

RXFP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RXFP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992108
CAS No.: 3061442-66-5
Synonyms: RELAX10

Research Areas:  

Cardiovascular Disease

Efadirelaxin alfa (RELAX10) is a highly selective agonist of relaxin/insulin-like family peptide receptor RXFP1. After subcutaneous administration in animal experiments, Efadirelaxin alfa exhibits a significantly prolonged terminal half-life (7 days in mice, 3.75 days in rats), and shows no activity against related receptors such as RXFP2 and RXFP3. Efadirelaxin alfa has significant anti-cardiac hypertrophy and anti-fibrotic effects. Efadirelaxin alfa effectively attenuates and reverses cardiac hypertrophy and collagen deposition by regulating the TGF-β1/Smad2 and AKT/eNOS signaling pathways. Efadirelaxin alfa improves cardiac systolic function without causing fluctuations in blood pressure or heart rate, demonstrating favorable safety. Efadirelaxin alfa is currently mainly used in studies related to heart failure .
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