2 Results for "

Radicicol

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Radicicol" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N6769
CAS No.: 12772-57-5
Synonyms: Monorden
Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM .
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Cat. No.: HY-12933
CAS No.: 911398-13-5
Target:  

HSP

Research Areas:  

Cancer

BIIB-028 is an orally active inhibitor for heat shock protein 90 (Hsp90). BIIB-028 targets the ATP-binding site of Hsp90, disrupts the function of Hsp90, leads to the degradation of client proteins, that are crucial for cancer cell survival and proliferation .
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