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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
SGC-7901
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "SGC-7901" in MCE Product Catalog:
9
9 Publications Verification
Synonyms: Mepacrine dihydrochloride; SN-390 dihydrochloride
Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis .
9
9 Publications Verification
Synonyms: Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate
Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis .
3
Research Areas:
Sertindole (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells .
3
3 Cited Publications
Cat. No.: HY-N4185
CAS No.: 61153-77-3
1
1
1 Cited Publications
Cat. No.: HY-W015084
CAS No.: 14901-07-6
Category:
Viola odorata Linn. Ketones, Aldehydes, Acids Violaceae Plants Disease Research Fields Cancer
Target:
1
1
1 Cited Publications
Cat. No.: HY-W006957
CAS No.: 4338-48-1
Target:
Nucleoside Antimetabolite/Analog Insecticide NF-κB TGF-beta/Smad Reactive Oxygen Species (ROS) Apoptosis Autophagy Mitochondrial Metabolism SOD
Research Areas:
N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. N6-(2-Hydroxyethyl)adenosine inhibits NF-κB/Smad signaling pathway, exhibits anti-hyperglycemia, antioxidant, antitumor and anti-inflammatory and insecticidal activities. N6-(2-Hydroxyethyl)adenosine is orally active .
1
1 Cited Publications
Cat. No.: HY-N0608
CAS No.: 171485-39-5
1
1 Cited Publications
MY-1076 is an inhibitor of YAP. MY-1076 induces YAP degradation and cell apoptosis. MY-1076 inhibits MGC-803, SGC-7901, HCT-116 and KYSE450 cells proliferation with IC50 s of 0.019, 0.017, 0.020 and 0.044 μM, respectively .
Cat. No.: HY-W015084A
CAS No.: 79-77-6
Synonyms: β-Lonone
Target:
Cat. No.: HY-N4148
CAS No.: 108648-07-3
Category:
Simple Phenylpropanols Scrophulariaceae Phenols Polyphenols Phenylpropanoids Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W001084
CAS No.: 14199-15-6
Target:
Cat. No.: HY-N6651
CAS No.: 22550-15-8
Cat. No.: HY-N7980
CAS No.: 2170211-22-8
Category:
Quinones Rubia podantha Rubiaceae Plants Disease Research Fields Naphthalene Quinones Cancer
Target:
Cat. No.: HY-N10201
CAS No.: 1221163-94-5
Target:
Cat. No.: HY-N11546
CAS No.: 30994-75-3
Target:
Cat. No.: HY-161351
STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells .
Cat. No.: HY-124398
CAS No.: 591242-70-5
GL-1196 is an inhibitor of PAK4. GL-1196 can suppress the proliferation and invasion of gastric cancer cells. GL-1196 inhibits PAK4-mediated signaling pathways. GL-1196 can hinder the proliferation of human gastric cancer cells through suppressing PAK4/c-Src/EGFR/CyclinD1 and CDK4/6. GL-1196 can reduce filamentous pseudopodia formation and induce filamentous pseudopodia formation and promote cell elongation in SGC7901 and BGC823 cells. GL-1196 can be studied in anti-cancer research .
Cat. No.: HY-176162
Research Areas:
BJ-13 is a reactive oxygen species (ROS) inducer that can lead to mitochondrial membrane potential collapse and caspase-dependent apoptosis. BJ-13 inhibits the proliferation of SGC-7901, U-87MG, and HepG-2 cancer cells (IC50 values of 15.33, 27.18, and 20.44 nM, respectively). BJ-13 can be used in the study of gastric cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
