2. Apoptosis
  3. Apoptosis
  4. Dracorhodin perchlorate

Dracorhodin perchlorate  (Synonyms: Dracohodin perochlorate)

Cat. No.: HY-N0726 Purity: 99.02%
COA Handling Instructions

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Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation and induces cell cycle arrest and apoptosis.

For research use only. We do not sell to patients.

Dracorhodin perchlorate Chemical Structure

Dracorhodin perchlorate Chemical Structure

CAS No. : 125536-25-6

Size Price Stock Quantity
1 mg USD 33 In-stock
5 mg USD 70 In-stock
10 mg USD 120 In-stock
20 mg USD 200 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Dracorhodin perchlorate:

Dracorhodin perchlorate Related Antibodies

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Description

Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation and induces cell cycle arrest and apoptosis[1][2].

Molecular Weight

366.75

Formula

C17H15ClO7
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

CC1=C(OC)C2=CC=C(C3=CC=CC=C3)[O+]=C2C=C1O.O=Cl(=O)([O-])=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (272.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7267 mL 13.6333 mL 27.2665 mL
5 mM 0.5453 mL 2.7267 mL 5.4533 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: 2.5 mg/mL (6.82 mM); Suspended solution; Need ultrasonic

    This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.02%

COA (247 KB) HNMR (269 KB) RP-HPLC (278 KB) MS (70 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7267 mL 13.6333 mL 27.2665 mL 68.1663 mL
5 mM 0.5453 mL 2.7267 mL 5.4533 mL 13.6333 mL
10 mM 0.2727 mL 1.3633 mL 2.7267 mL 6.8166 mL
15 mM 0.1818 mL 0.9089 mL 1.8178 mL 4.5444 mL
20 mM 0.1363 mL 0.6817 mL 1.3633 mL 3.4083 mL
25 mM 0.1091 mL 0.5453 mL 1.0907 mL 2.7267 mL
30 mM 0.0909 mL 0.4544 mL 0.9089 mL 2.2722 mL
40 mM 0.0682 mL 0.3408 mL 0.6817 mL 1.7042 mL
50 mM 0.0545 mL 0.2727 mL 0.5453 mL 1.3633 mL
60 mM 0.0454 mL 0.2272 mL 0.4544 mL 1.1361 mL
80 mM 0.0341 mL 0.1704 mL 0.3408 mL 0.8521 mL
100 mM 0.0273 mL 0.1363 mL 0.2727 mL 0.6817 mL
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Dracorhodin perchlorate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dracorhodin125536-25-6Dracohodin perochlorateApoptosisInhibitorinhibitorinhibit

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