1 Result for "

SHP1B

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHP1B" in MCE Product Catalog:

Art. -Nr.: HY-152208
CAS. Nr.: 2907659-86-1
Target:  

SHP1 SHP2

Forschungsgebiete:  

Cancer

BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 μM, 40.71 μM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes [1].
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