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Results for "

STK33

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Antibodies

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13495
    ML281
    2 Publications Verification

    		 STK33 PKA Aurora Kinase Bcl-2 Family Apoptosis Metabolic Disease Cancer
    ML281 is a highly selective inhibitor of serine/threonine kinase 33 (STK33) with an IC50 value of 14 nM. ML281 shows 700-fold selectivity over PKA and 550-fold over AurB. ML281 exerts core mechanism by inhibiting STK33: in small cell lung cancer, ML281 downregulates RPS6/BAD signaling phosphorylation, induces apoptosis, and suppresses proliferation, invasion . ML281 reduces STK33-mediated 4-hydroxyphenylpyruvate dioxygenase (HPD) phosphorylation in tyrosinemia . ML281 is suitable for research on STK33 function, KRAS mutation-related cancers (pancreatic cancer, colon cancer, lung adenocarcinoma, etc.), small cell lung cancer, and tyrosinemia-related damage
    ML281
  • HY-114331
    DLK-IN-1

    		MAP3K FLT3 PAK STK33 Trk Receptor Neurological Disease
    DLK-IN-1 (Compound 14) is an orally active, blood-brain barrier-penetrable and selective inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with a Ki value of 3 nM. DLK-IN-1 inhibits Flt3, PAK4, STK33 and TrkA. DLK-IN-1 reduces p-c-Jun. DLK-IN-1 can be used in Alzheimer's disease research .
    DLK-IN-1
  • HY-13498
    BRD-8899

    		STK33 Cancer
    BRD-8899 is a STK33 inhibitor, with an IC50 of 11 nM .
    BRD-8899
  • HY-162565
    CDD-2807

    		STK33 CDK RET Endocrinology
    CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive .
    CDD-2807
  • HY-13497
    STK33-IN-1

    		STK33 Cancer
    STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM .
    STK33-IN-1
  • HY-E70864
    STK33 Recombinant Human Active Protein Kinase

    		CaMK Metabolic Disease
    STK33 is clearly related to the canonical kinases from the CAMK group. STK33 could be involved in the normal development of heart and other organs in embryonic and fetal stages. STK33 Recombinant Human Active Protein Kinase is a recombinant STK33 protein that can be used to study STK33-related functions .
    STK33 Recombinant Human Active Protein Kinase
  • HY-RS13935
    STK33 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    STK33 Human Pre-designed siRNA Set A contains three designed siRNAs for STK33 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    STK33 Human Pre-designed siRNA Set A
    STK33 Human Pre-designed siRNA Set A
  • HY-RS18082
    Stk33 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Stk33 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Stk33 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Stk33 Mouse Pre-designed siRNA Set A
    Stk33 Mouse Pre-designed siRNA Set A
  • HY-176885
    CDD-2211

    		STK33 RET Others
    CDD-2211 is a STK33 inhibitor, with a Kd of 0.018 nM and an IC50 of 5 nM. CDD-2211 has relatively weak inhibitory effects on off-target kinases, with IC50 values of 115 nM for CLK1, 48 nM for CLK2, 187 nM for CLK4, and 78 nM for RET. CDD-2211 can be used for the study of contraception .
    CDD-2211
  • HY-176885A
    CDD-2212

    		STK33 RET Others
    CDD-2212 is a STK33 inhibitor, with a Kd of 1.9 nM and an IC50 of 999 nM. CDD-2212 has relatively weak inhibitory effects on off-target kinases, with IC50 values of 3223 nM for CLK1, 1555 nM for CLK2, 5884 nM for CLK4, and 1093 nM for RET. CDD-2212 can be used for the study of contraception .
    CDD-2212
  • HY-176884
    CDD-2110

    		STK33 RET Others
    CDD-2210 is a STK33 inhibitor, with a Kd of 0.1 nM and an IC50 of 38 nM. CDD-2210 has relatively weak inhibitory effects on off-target kinases, with IC50 values of 1209 nM for CLK1, 917 nM for CLK2, 544 nM for CLK4, and 746 nM for RET. CDD-2210 can be used for the study of contraception .
    CDD-2110

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