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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
STRAD
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "STRAD" in MCE Product Catalog:
Cat. No.: HY-RS13959
Target:
Research Areas:
STRADA Human Pre-designed siRNA Set A contains three designed siRNAs for STRADA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703377
Synonyms: STRADA; STE20-Related Kinase Adaptor Alpha; STE20 Related Adaptor Alpha; STE20-Related Adapter Protein; STRAD; STE20-Like Pseudokinase; LYK5; STRAD Alpha; STE20-Related Kinase Adapter Protein Alpha; STLK5; NY-BR-96; Protein Kinase LYK5; Stlk; PMSE; Serolo
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-189758
CAS No.: 2684270-22-0
Research Areas:
SMALS-329 is an LKB1 activator with EC50 = 8.5 μM. SMALS-329 binds to the ATP-binding pocket of STRADα and enhances the binding of the LKB1-STRAD-MO25 trimeric complex as well as the thermal stability of STRAD and LKB1. SMALS-329 enhances LKB1 kinase catalytic activity and promotes phosphorylation of downstream AMPK and SIK family substrates. SMALS-329 inhibits proliferation of multiple tumor cell lines harboring wild-type LKB1 and induces cell cycle arrest. SMALS-329 can be used for research on LKB1-related diseases, such as cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
