2 Results for "

Secalonic acid D

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Secalonic acid D" in MCE Product Catalog:

Cat. No.: HY-N11576
CAS No.: 35287-69-5
Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-β, and degrades β-catenin. Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis .
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Cat. No.: HY-N15380
CAS No.: 2265910-52-7
4,4′-Secalonic acid D (Compound 12) is a PARP1 inhibitor. 4,4′-Secalonic acid D induces the accumulation of ROS and DNA damage, activates the caspase-3/GSDME pathway, and triggers apoptosis and pyroptosis of tumor cells by inhibiting PARP1. 4,4′-Secalonic acid D has anti-tumor activity .
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