2 Results for "

Secondary mutation

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Secondary mutation" in MCE Product Catalog:

Cat. No.: HY-158265
Target:  

FLT3

Research Areas:  

Cancer

FLT3D835Y/F691L-IN-1 (compd 8v) is an orally active inhibitor of FLT3 3-tyrosine kinase domain D835Y/F691L secondary mutations with IC50s of 1.5 and 9.7 nM. FLT3D835Y/F691L-IN-1 can be used for acute myeloid leukemia research .
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Cat. No.: HY-143434
CAS No.: 2648799-49-7
Target:  

FLT3

Research Areas:  

Cancer

FLT3/D835Y-IN-1 (compound 13a) is a orally active, potent and selective FLT3 and FLT3/D835Y inhibitor, with IC50 values of 0.26 nM and 0.18 nM, respectively. FLT3/D835Y-IN-1 also blocks tumor growth, has anticancer efficacy, and can be used to research for AML (acute myeloid leukemia) .
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