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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Setidegrasib
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Setidegrasib" in MCE Product Catalog:
Synonyms: ASP-3082; KRAS G12D inhibitor 17
Setidegrasib (ASP-3082) is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib suppresses p-ERK, p-AKT, p-S6 levels in AsPC-1 cells. Setidegrasib exhibits anti-tumor activity in various cancer xenograft models in mice. Setidegrasib can be used in studies involving KRAS(G12D)-mutated solid tumors, such as non-small cell lung cancer .
Cat. No.: HY-168701
Research Areas:
E3 Ligase Ligand-linker Conjugate 149 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 149 can be used to synthesize Setidegrasib (HY-148273) .
Cat. No.: HY-168700
Research Areas:
KRAS G12D ligand-2 is a Ligand for Target Protein for PROTAC. KRAS G12D ligand-2 can be used to synthesize Setidegrasib (HY-148273) .
Cat. No.: HY-168699
Target:
Research Areas:
E3 ligase Ligand 45 is an E3 ligase ligand that can be used to synthesize the PROTAC degrader Setidegrasib (HY-148273) for Ras .
Cat. No.: HY-168698
CAS No.: 2149801-20-5
Target:
Research Areas:
(4-(1H-1,2,3-Triazol-4-yl)phenyl)methanol is a PROTAC Linker. (4-(1H-1,2,3-Triazol-4-yl)phenyl)methanol can be used to synthesize PROTAC Setidegrasib (HY-148273) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
