1 Result for "

TAS4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TAS4" in MCE Product Catalog:

Cat. No.: HY-115860
CAS No.: 794544-99-3
Target:  

iGluR

Research Areas:  

Neurological Disease

TAS-4 is a potent and selective mGluR4 positive allosteric modulator with significant anti-Parkinson's disease activity. TAS-4 is able to show efficacy when used alone or in combination with l-DOPA. TAS-4 is able to reverse haloperidol-induced spasticity when administered alone. TAS-4 enhances the contralateral rotation behavior induced by l-DOPA in a dose-dependent manner. TAS-4 combined with low-dose l-DOPA shows anti-Parkinson's effects similar to full-dose l-DOPA without exacerbating abnormal motor side effects .
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