2 Results for "

TED

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TED" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-125269
CAS No.: 2378626-29-8
Purity:  98.97%
Target:  

YAP

Research Areas:  

Cancer

TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 μM for TEAD4⋅Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a Ki of 10.3 μM. TED-347 blocks TEAD transcriptional activity and has antitumor activity .
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Cat. No.: HY-P991255

Target:  

IGF-1R

Research Areas:  

Inflammation/Immunology

VRDN-002 is a human monoclonal antibody (mAb) targeting IGF1R/CD221. VRDN-002 reduces inflammation and proptosis in thyroid eye disease (TED). VPI-2690B can be used in Graves ophthalmopathy research .
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