5 Results for "

Thiothixene

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Thiothixene" in MCE Product Catalog:

Cat. No.: HY-108324
CAS No.: 3313-26-6
Purity:  99.84%
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.
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Cat. No.: HY-A0139
CAS No.: 5591-45-7
Synonyms: NSC 108165; Navan; Navane
Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis=0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis=15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis=3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats.3 Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior.
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Cat. No.: HY-108324A
CAS No.: 49746-04-5
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Thiothixene hydrochloride is an antipsychotic agent. Thiothixene hydrochloride can be used for borderline and schizotypal disorder research .
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Cat. No.: HY-108324R
CAS No.: 3313-26-6
Research Areas:  

Neurological Disease

(Z)-Thiothixene (Standard) is the analytical standard of (Z)-Thiothixene. This product is intended for research and analytical applications. (Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.
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Cat. No.: HY-W748758
Synonyms: NSC 108165-d8; Navan-d8; Navane-d8
(Z)-Thiothixene-d8 (NSC 108165-d8; Navan-d8; Navane-d8) is the deuterium labeled Thiothixene (HY-A0139). Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis=0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis=15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis=3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats.3 Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior.
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