1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. (Z)-Thiothixene

(Z)-Thiothixene 

Cat. No.: HY-108324 Purity: 99.14%
Handling Instructions

(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.

For research use only. We do not sell to patients.

(Z)-Thiothixene Chemical Structure

(Z)-Thiothixene Chemical Structure

CAS No. : 3313-26-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 119 In-stock
Estimated Time of Arrival: December 31
5 mg USD 108 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
25 mg USD 348 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.

IC50 & Target

serotonergic receptor[1]

In Vitro

(Z)-Thiothixene is capable of promoting cell survival and/or plasticity, and/or inhibiting cell death, especially when a toxic agent is exposed to the cells, including neuronal cells[1]. (Z)-Thiothixene is a Z (cis) isomer of thiothixene, as well as synthetic precursor and degradant[2].

Molecular Weight

443.63

Formula

C₂₃H₂₉N₃O₂S₂

CAS No.

3313-26-6

SMILES

O=S(C1=CC(/C2=C\CCN3CCN(C)CC3)=C(SC4=C2C=CC=C4)C=C1)(N(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (28.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2541 mL 11.2707 mL 22.5413 mL
5 mM 0.4508 mL 2.2541 mL 4.5083 mL
10 mM 0.2254 mL 1.1271 mL 2.2541 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.25 mg/mL (2.82 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.25 mg/mL (2.82 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 1.25 mg/mL (2.82 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product name:
(Z)-Thiothixene
Cat. No.:
HY-108324
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