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Trans-translation

" in MedChemExpress (MCE) Product Catalog:
製品番号 製品名 Target 研究分野 構造式
  • HY-101866
    KKL-35

    		Bacterial Infection
    KKL-35 is a trans-translation tagging reaction inhibitor with an IC50 of 0.9 μM.
    KKL-35
  • HY-112565
    MBX-4132
    2 Publications Verification

    		 Bacterial Infection
    MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
    MBX-4132
  • HY-146446
    PXYC1

    		Bacterial Antibiotic Infection
    PXYC1 is a ribosomal protein S1 (RpsA) antagonist with Kds of 0.81 and 0.31 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYC1
  • HY-146451
    PXYC12

    		Bacterial Antibiotic Infection
    PXYC12 is a ribosomal protein S1 (RpsA) antagonist with Kds of 2.67 and 4.67 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYC12
  • HY-146448
    PXYD3

    		Bacterial Infection
    PXYD3 is a ribosomal protein S1 (RpsA) antagonist with Kds of 5.66 and 6.91 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYD3
  • HY-146450
    PXYC2

    		Bacterial Antibiotic Infection
    PXYC2 is a ribosomal protein S1 (RpsA) antagonist with Kds of 6.35 and 5.11 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYC2
  • HY-146447
    PXYC13

    		Bacterial Antibiotic Infection
    PXYC13 is a ribosomal protein S1 (RpsA) antagonist with Kds of 7.61 and 8.50 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYC13
  • HY-146449
    PXYD4

    		Bacterial Antibiotic Infection
    PXYD4 is a ribosomal protein S1 (RpsA) antagonist with Kds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
    PXYD4
  • HY-183851
    KKL-55

    		Bacterial mRNA Infection
    KKL-55 is a broad-spectrum antibacterial agent that inhibits the trans-translation pathway and the ClpXP protease. KKL-55 suppresses trans-translation of non-stop mRNA, interferes with the binding of EF-Tu to tmRNA, and inhibits the proteolysis of substrates by ClpXP. KKL-55 blocks spore germination of Bacillus anthracis and protects macrophages from damage induced by anthrax toxin. By virtue of its inhibitory effect on ClpXP, KKL-55 synergistically enhances the antibacterial activity of antibiotics against drug-resistant Staphylococcus aureus. KKL-55 can be used in studies related to bacterial infections .
    KKL-55
  • HY-146446R
    PXYC1 (Standard)

    		Reference Standards Bacterial Antibiotic Infection
    Maltopentaose (Standard) is the analytical standard of Maltopentaose. This product is intended for research and analytical applications. Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin.
    PXYC1 (Standard)
  • HY-101866R
    KKL-35 (Standard)

    		Reference Standards Bacterial Infection
    KKL-35 (Standard) is the analytical standard of KKL-35 (HY-101866). This product is intended for research and analytical applications. KKL-35 is a trans-translation tagging reaction inhibitor with an IC50 of 0.9 μM.
    KKL-35 (Standard)

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