4 Results for "

TryR

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "TryR" in MCE Product Catalog:

Cat. No.: HY-128170
CAS No.: 2527-03-9
Purity:  98.71%
Target:  

Parasite

Research Areas:  

Infection

Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis .
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Cat. No.: HY-W043676
CAS No.: 1210-34-0
Research Areas:  

Infection

Dibenzosuberol (Compound 2) is a key intermediate in the synthesis of compounds associated with inhibiting Trypanosoma thiol reductase (TryR). Dibenzosuberol also shows inhibition of T. brucei with an EC50 value of 51.3 μM. Dibenzosuberol is also an impurity of Amitriptyline (HY-B0527) .
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Cat. No.: HY-W008356
CAS No.: 137553-42-5
Target:  

Drug Intermediate

Research Areas:  

Infection Metabolic Disease

2-Fluoro-4-iodobenzonitrile is a building block, which can be used to synthesize L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile can also be used to synthesize transient receptor potential ankyrin 1 (TRPA1) antagonists .
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Cat. No.: HY-129278
CAS No.: 24185-51-1
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM .
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