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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
VUF 11207
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "VUF 11207" in MCE Product Catalog:
3
3 Cited Publications
Research Areas:
VUF11207 is a potent, selective, and orally active CXCR7/ACKR3 agonist (pKi = 8.1). VUF11207 specifically activates CXCR7/ACKR3, recruits β-arrestin, and induces receptor internalization, while downregulating the pro-inflammatory, pro-osteoclastogenic, and tumor immunosuppressive signaling mediated by the CXCL12-CXCR4 axis. VUF11207 can be used for research on glioblastoma, hypertension, and venous thrombosis .
3
3 Cited Publications
Research Areas:
VUF11207 fumarate is a potent, selective, and orally active CXCR7/ACKR3 agonist (pKi = 8.1). VUF11207 fumarate specifically activates CXCR7/ACKR3, recruits β-arrestin, and induces receptor internalization, while downregulating the pro-inflammatory, pro-osteoclastogenic, and tumor immunosuppressive signaling mediated by the CXCL12-CXCR4 axis. VUF11207 fumarate can be used for research on glioblastoma, hypertension, and venous thrombosis .
Cat. No.: HY-115615
CAS No.: 1492153-74-8
VUF11207 TFA is a potent, selective, and orally active CXCR7/ACKR3 agonist (pKi = 8.1). VUF11207 TFA specifically activates CXCR7/ACKR3, recruits β-arrestin, and induces receptor internalization, while downregulating the pro-inflammatory, pro-osteoclastogenic, and tumor immunosuppressive signaling mediated by the CXCL12-CXCR4 axis. VUF11207 TFA can be used for research on glioblastoma, hypertension, and venous thrombosis .
Cat. No.: HY-110318R
CAS No.: 1785665-61-3
Target:
VUF11207 fumarate Standard is the analytical standard of VUF11207 fumarate (HY-110318). This product is intended for research and analytical applications. VUF11207 fumarate is a potent, selective, and orally active CXCR7/ACKR3 agonist (pKi = 8.1). VUF11207 fumarate specifically activates CXCR7/ACKR3, recruits β-arrestin, and induces receptor internalization, while downregulating the pro-inflammatory, pro-osteoclastogenic, and tumor immunosuppressive signaling mediated by the CXCL12-CXCR4 axis. VUF11207 fumarate can be used for research on glioblastoma, hypertension, and venous thrombosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
