1 Result for "

ZT55

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZT55" in MCE Product Catalog:

Cat. No.: HY-124727
CAS No.: 2138488-38-5
Purity:  99.51%
Target:  

JAK Apoptosis

Research Areas:  

Cancer

ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 μM. ZT55 inhibits the proliferation of JAK2 V617F-expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia .
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