2 Results for "

Zilovertamab

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Zilovertamab" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99201
CAS No.: 2485779-13-1
Synonyms: UC-961; Cirmtuzumab

Target:  

ROR Wnt

Research Areas:  

Cancer

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling .
loading...
    loading...
Cat. No.: HY-P99956
Synonyms: VLS-101; MK-2140

Research Areas:  

Cancer

Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–agent conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer .
loading...
    loading...