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3 Results for "
aTAG4531
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "aTAG4531" in MCE Product Catalog:
Cat. No.: HY-163168
CAS No.: 2412985-00-1
Synonyms: CFT-4531
Target:
Research Areas:
aTAG 4531 is a PROTAC-class degrader that induces the degradation of the MTH1/aTAG fusion protein by recruiting cereblon, with a DC50 of 0.28 nM in Jurkat cells. aTAG 4531 inhibits MTH1 enzymatic activity, with a Ki of 1.8 nM. aTAG 4531 rapidly, selectively and reversibly regulates SMART-CAR protein levels, CAR-mediated target cell killing and IL-2 release, and is applicable both in vitro and in vivo. aTAG 4531 can be used in studies of targeted protein degradation, target validation and CAR-T activity regulation .
Cat. No.: HY-134725
CAS No.: 2412987-06-3
Research Areas:
MTH1 degrader-1, a MTH1 aTAG inhibitor, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). MTH1 degrader-1 can be used for synthesis PROTAC aTAG 4531 (HY-163168) .
Cat. No.: HY-169368
CAS No.: 2412988-59-9
Research Areas:
Thalidomide-O-Triazole-C4-amino is an E3 ligase ligand-linker conjugate. Thalidomide-O-Triazole-C4-amino can be used to synthesize aTAG 4531 (HY-163168) .
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