69 Results for "

amyloid-β peptide

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "amyloid-β peptide" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0061
CAS No.: 4046-02-0
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .
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2
2 Cited Publications
Cat. No.: HY-100200
CAS No.: 307538-42-7
Purity:  99.92%
Target:  

Autophagy

Research Areas:  

Cancer

SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
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1
1 Cited Publications
Cat. No.: HY-P1362
CAS No.: 317366-82-8
Synonyms: amyloid β peptide (42-1)(human)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). Its active form, β-Amyloid (1-42), may play a key role in the pathogenesis of Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-N2319
CAS No.: 24730-10-7
Synonyms: DHEC mesylate
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively .
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1
1 Cited Publications
Cat. No.: HY-P704352
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APP; PreA4; Prev. AD1; CVAP; Alzheimer Disease amyloid A4 Protein Homolog; Beta-amyloid Precursor Protein; amyloid-Beta Precursor Protein; Testicular Tissue Protein Li 2; amyloid Precursor Protein; Beta-amyloid peptide(1-40); Alpha-SAPP; Beta-amyloid Pept
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99317
CAS No.: 955085-14-0
Synonyms: LY-2062430

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Solanezumab (LY-2062430) is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β () peptide. Solanezumab binds to the mid-domain of monomeric amyloid-beta to slow brain amyloid accumulation. Solanezumab can be used for the research of Alzheimer’s disease .
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Cat. No.: HY-125616
CAS No.: 299157-54-3
Purity:  99.69%
Synonyms: Biotinyl-GHK; Bio-GHK
Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases .
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Cat. No.: HY-17631A
CAS No.: 519187-97-4
Synonyms: T-817 maleate; T-817MA
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides ().
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Cat. No.: HY-P5124
CAS No.: 153247-40-6
Synonyms: KLVFF
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility) .
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Cat. No.: HY-P5905
Synonyms: Citrullinated Aβ (1-42); Citrullinated Aβ42
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Citrullinated amyloid-β (1-42) peptide (human) (Citrullinated Aβ (1-42)) is a modified form of β-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified β-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified Aβ42, it forms protofibrils comprised of parallel β-sheets .
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Cat. No.: HY-P1962
CAS No.: 350228-37-4
Synonyms: [Asn670, Sta671, Val672]-amyloid β peptide (662-675)
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase) .
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Cat. No.: HY-P10040
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Gln22)β-Amyloid (1-40) human is an amyloid beta protein (Aβ)-containing peptide used in Alzheimer's disease research .
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Cat. No.: HY-P1047
CAS No.: 182912-74-9
Synonyms: [Pro18, Asp21] β-amyloid (17-21)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Sheet Breaker Peptide iAβ5 is an effective brain amyloid-β (Abeta) degrader. Abeta deposits are associated with Alzheimer's disease (AD), and the related toxicity arises from its β-sheet conformation and aggregation. β-Sheet Breaker Peptide iAβ5 can repeatedly induce the degradation of fibrillary amyloid deposits in vivo. Therefore, β-Sheet Breaker Peptide iAβ5 can prevent and/or reverse neuronal contraction caused by Abeta and reduce the range of interleukin IL-1beta positive microglial-like cells around Abeta deposits. β-Sheet Breaker Peptide iAβ5 can reduce the size and/or number of brain amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 is labeled with a hydrophobic benzyl alcohol (HBA) tag and shows a bright blue color under acidic conditions, which can be used for quantitative determination.
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Cat. No.: HY-N8161
CAS No.: 25615-14-9
Synonyms: Kaempferol 3,7-diglucoside
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .
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Cat. No.: HY-P1362F
Synonyms: Cy5-amyloid β peptide (42-1)(human) Tris
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptideex= 633 nm and λem= 670 nm) . β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). Its active form, β-Amyloid (1-42), may play a key role in the pathogenesis of Alzheimer's disease.
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Cat. No.: HY-P3244
CAS No.: 342877-55-8
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

D-KLVFFA is the inhibitor of Amyloid-β assembly, with the IC50 of 2.6 μM, that can be used in Alzheimer's disease study .
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Cat. No.: HY-P4885
CAS No.: 161818-04-8
Synonyms: AβpE3-40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a minor amounts of pyroglutamate-modified isolated from from 24-month-old Amyloid precursor protein (APP) transgenic Mice .
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Cat. No.: HY-P1517
CAS No.: 149385-65-9
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.
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Cat. No.: HY-P2549
CAS No.: 183906-14-1
Target:  

Fluorescent Dye

Research Areas:  

Neurological Disease

Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.
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Cat. No.: HY-P5906
Synonyms: Citrullinated Aβ (1-40); Citrullinated Aβ40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Citrullinated amyloid-β (1-40) peptide (human) (Citrullinated Aβ (1-40)) is a modified form of β-Amyloid (1-40) (HY-P0265) with a citrullination at the Arg5 site. Citrullinated amyloid-β (1-40) peptide (human) exhibits increased transient formation of soluble oligomers and insoluble aggregates composed of distorted parallel β-sheets compared with unmodified β-Amyloid (1-40) .
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