1. Neuronal Signaling
  2. Amyloid-β

β-Amyloid 31-35 

Cat. No.: HY-P1517
Handling Instructions

β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

β-Amyloid 31-35 Chemical Structure

β-Amyloid 31-35 Chemical Structure

CAS No. : 149385-65-9

Size Price Stock
1 mg USD 70 Get quote
5 mg USD 140 Get quote
10 mg USD 210 Get quote

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.

In Vitro

β-Amyloid (31-35) is a functional cytotoxic domain of Aβ peptide. β-Amyloid (31-35) increases the phosphorylation of biotinylated Aβ(1-40), enhances CDK-1 activity, and also inhibits binding of Aβ to cyclin B1. β-Amyloid (31-35) is cytotoxic, and such an effect can be inhibited by olomoucine in differentiated human teratocarcinoma cell line, Ntera 2/cl-D1 (NT-2) neurons[1]. β-Amyloid (31-35) shows cytotoxic effect on cerebellar granule cells (CGC). β-Amyloid (31-35) also increases caspase-3 activity in a time-dependent manner (4-24 h) at 40 μM[2].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8324 mL 9.1619 mL 18.3237 mL
5 mM 0.3665 mL 1.8324 mL 3.6647 mL
10 mM 0.1832 mL 0.9162 mL 1.8324 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

545.74

Formula

C₂₅H₄₇N₅O₆S

CAS No.

149385-65-9

Sequence

Ile-Ile-Gly-Leu-Met

Sequence Shortening

IIGLM

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
β-Amyloid 31-35
Cat. No.:
HY-P1517
Quantity:

β-Amyloid 31-35

Cat. No.: HY-P1517