Kaempferol-3,7-di-O-β-glucoside
Based on 1 Customer Validation
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research.
For research use only. We do not sell to patients.
- Purity: 99.59%
- CAS No.: 25615-14-9
- Formula: C27H30O16
- Molecular Weight:610.52
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
28.89 μM
Compound: 16
|
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
|
[PMID: 23149227] |
In Vitro
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside; 0.1, 100 μM) has effective inhibition in Aβ1-42 fibril formation. Kaempferol-3,7-di-O-β-glucoside has less neurotoxicity on the cultured SH-SY5Y cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25615-14-9
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Appearance Solid
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Molecular Weight 610.52
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Formula C27H30O16
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Color Off-white to light yellow
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SMILES
O=C1C(O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO)=C(C(C=C3)=CC=C3O)OC4=CC(O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O)CO)=CC(O)=C14
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Synonyms
Kaempferol 3,7-diglucoside
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)