29 Results for "

anti-hyperlipidemic

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "anti-hyperlipidemic" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B0388
CAS No.: 23288-49-5
Synonyms: DH-581
Probucol (DH-581) is an anti-hyperlipidemic agent. Probucol activates glutathione peroxidase. Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels. Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer, neurological, and metabolism-related diseases .
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3
3 Cited Publications
Cat. No.: HY-14739
CAS No.: 856676-23-8
Purity:  99.86%
Synonyms: ABT-335
Target:  

PPAR COX

Research Areas:  

Cardiovascular Disease

Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect .
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3
3 Cited Publications
Cat. No.: HY-N7676
CAS No.: 535-96-6
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
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2
2 Cited Publications
Cat. No.: HY-N2555
CAS No.: 4291-60-5
Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects .
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2
2 Cited Publications
Cat. No.: HY-N4137
CAS No.: 13850-16-3
Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .
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1
1 Cited Publications
Cat. No.: HY-122951
CAS No.: 560-66-7
Purity:  98.97%
Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms . And Eburicoic acid has antidiabetic and antihyperlipidemic effects .
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Cat. No.: HY-B1189
CAS No.: 503-49-1
Synonyms: Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases .
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Cat. No.: HY-N2923
CAS No.: 1616-93-9
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase .
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Cat. No.: HY-75625
CAS No.: 2237-36-7
Synonyms: 4-Methoxysalicylic Acid
2-Hydroxy-4-methoxybenzoic acid is an orally active inhibitor of MCT-1 and MCT-4, as well as a plant biomarker. 2-Hydroxy-4-methoxybenzoic acid can be isolated from roots. 2-Hydroxy-4-methoxybenzoic acid induces Apoptosis and loss of mitochondrial membrane potential. 2-Hydroxy-4-methoxybenzoic acid exhibits anticancer activity against breast cancer. 2-Hydroxy-4-methoxybenzoic acid normalizes lactic acid levels. 2-Hydroxy-4-methoxybenzoic acid neutralizes viper venom and attenuates its lethal, hemorrhagic, coagulant and anticoagulant activities in male albino mice. 2-Hydroxy-4-methoxybenzoic acid possesses antihyperlipidemic, antidiabetic and hepatoprotective activities .
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Cat. No.: HY-107396
CAS No.: 138046-43-2
Purity:  99.95%
Target:  

Acyltransferase

Research Areas:  

Cardiovascular Disease

YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .
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Cat. No.: HY-B0388R
CAS No.: 23288-49-5
Synonyms: DH-581 (Standard)
Research Areas:  

Metabolic Disease

Probucol (Standard) is the analytical standard of Probucol. This product is intended for research and analytical applications. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
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Cat. No.: HY-N8144
CAS No.: 95262-48-9
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis .
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Cat. No.: HY-W011334
CAS No.: 2380-27-0
Methyl 12-oxooctadecanoate is a fatty acid that can be isolated from the pulp of Livistona decipiens (Palmae), which has anti-hyperlipidemic and anti-ulcer activities .
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Cat. No.: HY-139134
CAS No.: 155730-92-0
S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research .
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Cat. No.: HY-156977
CAS No.: 55902-94-8
Target:  

PPAR

Research Areas:  

Cardiovascular Disease

Sitofibrate is a Clofibrate (HY-B0287) derivative. Sitofibrate is aperoxisome proliferator activated receptor-α (PPAR-α) agonist. Sitofibrate is an antihyperlipidemic agent .
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Cat. No.: HY-N7675A
CAS No.: 56389-87-8
(2R)-Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R)-Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities .
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Cat. No.: HY-N9010
CAS No.: 1528745-88-1
Target:  

Others

Chartarlactam A is a novel compound with anti-hyperlipidemic activity. Chartarlactam A exhibits inhibitory potential in HepG2 cells .
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Cat. No.: HY-B0388S1
Synonyms: DH-581-d6
Probucol-d6 is deuterium labeled Probucol. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
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Cat. No.: HY-B0388S
CAS No.: 1173019-29-8
Probucol- 13C3 is the 13C-labeled Probucol. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
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Cat. No.: HY-N2555R
CAS No.: 4291-60-5
Tilianin (Standard) is the analytical standard of Tilianin. This product is intended for research and analytical applications. Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects .
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