Eburicoic acid
Based on 1 publication(s) in Google Scholar
Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. And Eburicoic acid has antidiabetic and antihyperlipidemic effects.
For research use only. We do not sell to patients.
- Purity: 98.61%
- CAS No.: 560-66-7
- Formula: C31H50O3
- Molecular Weight:470.73
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Eburicoic acid
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
25 μM
Compound: 3
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Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
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[PMID: 15620242] |
| HL-60 | IC50 |
25 μM
Compound: 102
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Cytotoxicity against human HL60 cells
Cytotoxicity against human HL60 cells
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[PMID: 23092389] |
| MCF7 | IC50 |
>100 μM
Compound: 21
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Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
| Panel NCI-60 (60 carcinoma cell lines) | GI50 |
10 μM
Compound: Eburicoic acid
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Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program
Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program
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[PMID: 15743190] |
| SW480 | IC50 |
>100 μM
Compound: 21
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Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
| U-251 | IC50 |
>100 μM
Compound: 21
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Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
Chemical Information
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CAS No. 560-66-7
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Appearance Solid
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Molecular Weight 470.73
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Formula C31H50O3
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Color White to off-white
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SMILES
C[C@]12C3=C(CC[C@@]1([C@@](CC2)([H])[C@H](C(O)=O)CCC(C(C)C)=C)C)[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC3)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Mol Med Rep
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway. [Abstract]2025 Jul;32(1):186. PMID: 40314092
Solvent & Solubility
DMSO : 0.5 mg/mL (1.06 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Huang GJ, et al. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food Chem. 2013;141(3):3020-3027. [Content Brief]
[2]. Lin CH, et al. Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice. Int J Mol Sci. 2017;18(11):2314. Published 2017 Nov 2. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1244 mL | 10.6218 mL | 21.2436 mL | 53.1090 mL |
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