503-49-1
Chemical Structure
Meglutol
Synonym(s): Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid
- CAS No.: 503-49-1
- Formula:C6H10O5
- Molecular Weight:162.14
IUPAC Name: 3-hydroxy-3-methylpentanedioic acid
InChIKey: NPOAOTPXWNWTSH-UHFFFAOYSA-N
SMILES: O=C(O)CC(C)(O)CC(O)=O
Biological Activity: Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Meglutol | 99.95% | Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases. | ||||||||||||||||||||
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Meglutol (Standard) | ≥98% | Meglutol (Standard) is the analytical standard of Meglutol. This product is intended for research and analytical applications. Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases. | ||||||||||||||||||||
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Meglutol-d3 | 98.04% | Meglutol-d3 is the deuterium labeled Meglutol. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. | ||||||||||||||||||||
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