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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
antioxidant biomarkers
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "antioxidant biomarkers" in MCE Product Catalog:
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1 Cited Publications
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1 Cited Publications
Cat. No.: HY-113165
CAS No.: 25518-49-4
Target:
Target:
Research Areas:
Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway . Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death .
Cat. No.: HY-W984782
CAS No.: 523-64-8
Cat. No.: HY-W015229R
CAS No.: 830-96-6
Synonyms: Indole-3-propionic acid (Standard); 3-IPA (Standard)
Cat. No.: HY-135174
CAS No.: 13081-14-6
Synonyms: L-CySSG; CYSH-GSH
Research Areas:
L-Cysteine-glutathione disulfide (L-CySSG; CYSH-GSH) is a thiol-modified glutathione prodrug with antioxidant, anti-inflammatory, and oral activities. L-Cysteine-glutathione disulfide reduces the production of mitochondrial ROS, and alleviates oxidative stress, inflammatory responses, and elevated levels of hepatic enzymes. L-Cysteine-glutathione disulfide prevents liver injury in mice induced by high-fat diet or LPS. The expression level of L-Cysteine-glutathione disulfide changes during tuberculosis infection, so it can serve as a biomarker for pulmonary tuberculosis. L-Cysteine-glutathione disulfide is applicable to research on pulmonary tuberculosis, metabolic dysfunction-associated steatotic liver disease, and liver injury .
Cat. No.: HY-113165AS
Isobutyryl-L-carnitine-d3 chloride is the d3-labeled Isobutyryl-L-carnitine chloride (HY-113165A). Isobutyryl-L-carnitine chloride is a biomarker. Isobutyryl-L-carnitine chloride is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine chloride is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine chloride is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine chloride can be used in research on renal cell carcinoma .
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Copper (I) chloride is an oxidizable, photodegradable cuprous chloride halide that converts to a dark green mixture of copper (II) chloride and basic copper (II) chloride upon exposure to humid air. Copper (I) chloride is ecotoxic and induces oxidative stress in Paphia undulata, with persistent effects after exposure ceases. Copper (I) chloride finds applications in multiple fields such as chemical industry and metallurgy, serving as a catalyst for various reactions and being used in the preparation of the fungicide copper oxychloride .
Cat. No.: HY-113165AR
CAS No.: 6920-31-6
Cat. No.: HY-W700788
Isobutyryl-L-carnitine chloride-d6 is the d6-labeled Isobutyryl-L-carnitine chloride (HY-113165A). Isobutyryl-L-carnitine chloride is a biomarker. Isobutyryl-L-carnitine chloride is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine chloride is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine chloride is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine chloride can be used in research on renal cell carcinoma .
Cat. No.: HY-165316
CAS No.: 13699-45-1
Target:
NOD-like Receptor (NLR) Interleukin Related Reactive Oxygen Species (ROS) Caspase TNF Receptor Apoptosis
Research Areas:
Myristoyllysophosphatidylcholine is a NLRP3 inflammasome inhibitor with multiple activities including anti-inflammatory and antioxidant effects. Myristoyllysophosphatidylcholine inhibits LPS-induced NLRP3 inflammasome activation, reduces pro-inflammatory cytokine secretion, decreases ROS and MDA levels, alleviates lung tissue and cell damage, and mediates apoptosis. Myristoyllysophosphatidylcholine serves as a myristate donor for myristoylation of the Glucose-6-Phosphate Isomerase (GPI) anchor in Trypanosoma brucei and undergoes hydrolysis. Myristoyllysophosphatidylcholine acts as a biomarker for the severity of community-acquired pneumonia. Myristoyllysophosphatidylcholine can be used in research related to diseases such as community-acquired pneumonia and acute lung injury .
Cat. No.: HY-179502
Research Areas:
Anti-inflammatory agent 107 is an orally active anti-inflammatory agent. Anti-inflammatory agent 107 inhibits and NF-κB with a superior binding affinity of -9.4578 kcal/mol. Anti-inflammatory agent 107 reduces levels of inflammatory biomarkers (TNF-α, IL-6, INF-γ, NF-κβ, C-reactive protein and Erythrocyte Sedimentation Rate) and enhances the endogenous antioxidant defense system by elevating SOD (Superoxide Dismutase), CAT (Catalase) and GSH (Glutathione) activities. Anti-inflammatory agent 107 not induces liver toxicity and demonstrates hepatoprotective effects. Anti-inflammatory agent 107 dose-dependently ameliorates leukocyte infiltration and tissue edema. Anti-inflammatory agent 107 can be used for anti-inflammatory research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
