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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
auditory
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "auditory" in MCE Product Catalog:
Cat. No.: HY-P5163
CAS No.: 2843557-76-4
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NMB-1 is a cone peptide analog and a mechanosensitive current inhibitor. NMB-1 selectively inhibits sustained mechanically activated currents in sensory neurons, with an IC50 of 1 μM. NMB-1 inhibits mechanical pain. NMB-1 selectively raises high-threshold pressure nociceptive thresholds in rats. NMB-1 can be used in research on mechanically evoked pain and auditory dysfunction .
Cat. No.: HY-B0612B
CAS No.: 185197-71-1
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(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism .
Cat. No.: HY-157958
CAS No.: 3030040-34-4
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α7 nAChR modulator-3 (Compound 6p) is a α7 nAChR positive allosteric Modulator with a IC50 value of 1.3 μM. α7 nAChR Modulator-3 can be used to inhibit auditory gating defects in a mouse schizophrenic model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
