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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
183 Results for "
bacterial biofilms
" in MedChemExpress (MCE) Product Catalog:
Products (183)
183 Results for "bacterial biofilms" in MCE Product Catalog:
134
9
9 Cited Publications
Synonyms: c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium
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9
9 Cited Publications
Synonyms: c-di-GMP diammonium; cyclic diguanylate diammonium; 5GP-5GP diammonium
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3
3 Cited Publications
Cat. No.: HY-W001132
CAS No.: 120-72-9
Category:
Alkaloids Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields Indole Alkaloids
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3
3 Cited Publications
Cat. No.: HY-W015490
CAS No.: 130-15-4
Research Areas:
1,4-Naphthoquinone is an inhibitor with broad-spectrum inhibitory activity targeting DNA polymerase, NF-κB and monoamine oxidase (MAO-A/B), with antibacterial and anti-biofilm efficacy. 1,4-Naphthoquinone is a competitive inhibitor of MAO-B (Ki=1.4 μM) and a non-competitive inhibitor of MAO-A (Ki=7.7 μM). 1,4-Naphthoquinone inhibits DNA polymerase pol α, β, γ, δ, ε, λ with IC50 ranging from 5.57-128 μM. 1,4-Naphthoquinone inhibits tumor cell proliferation, induces apoptosis and necrosis, and has anti-angiogenic and anti-inflammatory activities by inducing oxidative stress, depleting glutathione (GSH), inhibiting DNA polymerase-mediated DNA synthesis and blocking NF-κB nuclear translocation. 1,4-Naphthoquinone can be used in anti-bacterial , anti-tumor and anti-inflammatory studies, including inhibition of melanoma and colon cancer cell growth and endothelial cell function, as well as LPS-induced inflammation models .
2
2 Cited Publications
Cat. No.: HY-P5641
CAS No.: 190324-47-1
Research Areas:
1
1 Cited Publications
Cat. No.: HY-W015580
CAS No.: 4695-62-9
1
1 Cited Publications
Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain .
1
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1
1
1 Cited Publications
Cat. No.: HY-Y1093S4
CAS No.: 1565868-21-4
1
1 Cited Publications
Cat. No.: HY-N6082
CAS No.: 34298-86-7
Cat. No.: HY-W133898
CAS No.: 73049-73-7
Category:
Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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Category:
Microorganisms Monophenols Ketones, Aldehydes, Acids Metabolic Disease Phenols Endogenous metabolite Disease Research Fields
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Research Areas:
Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds . Ethyl acetoacetate is an inhibitor of bacterial biofilm .
Cat. No.: HY-W012572
CAS No.: 351-50-8
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Research Areas:
D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu 2+) .
Cat. No.: HY-P10233A
Cat. No.: HY-N2947
CAS No.: 114567-34-9
Category:
Natural Products other families Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
