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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
carnitine palmitoyltransferase II
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "carnitine palmitoyltransferase II" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: (-)-Lauroylcarnitine
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-B2004
CAS No.: 130000-40-7
Research Areas:
Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Cat. No.: HY-113166R
CAS No.: 25518-54-1
Synonyms: (-)-Lauroylcarnitine (Standard)
Cat. No.: HY-B2004R
CAS No.: 130000-40-7
Research Areas:
Thifluzamide (Standard) is the analytical standard of Thifluzamide. This product is intended for research and analytical applications. Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Cat. No.: HY-P704989
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CPT2; CPTASE; Prev. CPT1; Testicular Secretory Protein Li 13; carnitine palmitoyltransferase II; IIAE4; carnitine O-palmitoyltransferase 2, Mitochondrial; carnitine palmitoyltransferase 2; CPT II
Species:
Human
Source:
E. coli
Cat. No.: HY-19150
CAS No.: 139681-18-8
Synonyms: FOX-988
Target:
Research Areas:
SDZ-FOX-988 (FOX-988) is an orally active antidiabetic agent. SDZ-FOX-988 sequesters mitochondrial coenzyme A to inhibit carnitine palmitoyltransferase II. SDZ-FOX-988 induces mitochondrial injury. SDZ-FOX-988 causes a decrease in serum β-hydroxybutyrate or glucose. SDZ-FOX-988 can be used in the research of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
