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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
coxsackievirus
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "coxsackievirus" in MCE Product Catalog:
11
Target:
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
2
2 Cited Publications
Target:
Research Areas:
TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .
1
1 Cited Publications
Cat. No.: HY-16561A
CAS No.: 61434-67-1
Target:
1
1 Cited Publications
Cat. No.: HY-P70052
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXADR; CVB3-Binding Protein; CXADR Cell Adhesion Molecule; HCVADR; CAR; HCAR; Coxsackie Virus And Adenovirus Receptor; 46 KD coxsackievirus And Adenovirus Receptor (CAR) Protein; coxsackievirus And Adenovirus Receptor; CXADR, Ig-Like Cell Adhesion Molecul
Species:
Mouse
Source:
HEK293
Target:
Research Areas:
DC07090 dihydrochloride is a low toxicity, potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 dihydrochloride could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM .
Target:
Pirlindole is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole can be used in research related to depression and enterovirus infections .
Cat. No.: HY-33015A
CAS No.: 49678-02-6
Synonyms: trans-p-Chlorocinnamaldehyde
Target:
Research Areas:
4-Chlorocinnamaldehyde (trans-p-Chlorocinnamaldehyde) is an antiviral agent. 4-Chlorocinnamaldehyde inhibits the replication of Coxsackievirus B3 in cardiomyocytes, but shows poor efficacy in animal experiments. 4-Chlorocinnamaldehyde can be used in studies related to viral myocarditis .
Cat. No.: HY-100679A
CAS No.: 207572-66-5
Target:
Pirlindole mesylate is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole mesylate inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole mesylate inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole mesylate shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole mesylate can be used in research related to depression and enterovirus infections .
Cat. No.: HY-100679S
CAS No.: 1801646-26-3
Cat. No.: HY-123517A
CAS No.: 879070-72-1
Target:
Research Areas:
DC07090 is a potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM .
Cat. No.: HY-W399940
CAS No.: 526-02-3
Category:
Cat. No.: HY-170412
Target:
Research Areas:
Cox B-IN-1 (7a) exhibits antiviral activity against Coxsackievirus B (Cox B). Cox B-IN-1 (7a) possesses dual activity that inhibits viral adsorption and replication. Cox B-IN-1 (7a) demonstrates substantial potential as an inhibitor of the 3C protease from coxsackievirus .
Cat. No.: HY-P11041
Target:
Research Areas:
Cat. No.: HY-100540A
CAS No.: 1005036-73-6
Synonyms: (Rac)-GCA
Target:
Research Areas:
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
Cat. No.: HY-P10802
Target:
Research Areas:
Cat. No.: HY-100679R
CAS No.: 60762-57-4
Pirlindole (Standard) is the analytical standard of Pirlindole (HY-100679). This product is intended for research and analytical applications. Pirlindole is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole can be used in research related to depression and enterovirus infections .
Cat. No.: HY-P706228
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CXADR; CVB3-Binding Protein; CXADR Cell Adhesion Molecule; HCVADR; CAR; HCAR; Coxsackie Virus And Adenovirus Receptor; 46 KD coxsackievirus And Adenovirus Receptor (CAR) Protein; coxsackievirus And Adenovirus Receptor; CXADR, Ig-Like Cell Adhesion Molecule; CXADR Ig-Like Cell Adhesion Molecule; CAR4/6; coxsackievirus B-Adenovirus Receptor
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P70049
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CXADR; CVB3-Binding Protein; CXADR Cell Adhesion Molecule; HCVADR; CAR; HCAR; Coxsackie Virus And Adenovirus Receptor; 46 KD coxsackievirus And Adenovirus Receptor (CAR) Protein; coxsackievirus And Adenovirus Receptor; CXADR, Ig-Like Cell Adhesion Molecul
Species:
Human
Source:
HEK293
Cat. No.: HY-P72364
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXADR; CVB3-Binding Protein; CXADR Cell Adhesion Molecule; HCVADR; CAR; HCAR; Coxsackie Virus And Adenovirus Receptor; 46 KD coxsackievirus And Adenovirus Receptor (CAR) Protein; coxsackievirus And Adenovirus Receptor; CXADR, Ig-Like Cell Adhesion Molecul
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
