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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
crystalline forms
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "crystalline forms" in MCE Product Catalog:
307
307 Publications Verification
Synonyms: GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate)
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis . This product is in solid form, a DMSO solvate, and a stable crystalline form.
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3 Cited Publications
Synonyms: Adonitol; Adonite
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1 Cited Publications
Cat. No.: HY-U00007A
CAS No.: 6935-63-3
Synonyms: Ba 2652 dihydrochloride; Stilbamidin dihydrochloride
Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
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UCB-6876 is a TNFα inhibitor. UCB-6876 specifically binds to the asymmetric crystalline form of TNF-α trimer with a KD of 22 μM. UCB-6876 is applicable to research related to autoimmune diseases (rheumatoid arthritis and Crohn's disease) .
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Cat. No.: HY-100582R
CAS No.: 488-81-3
Synonyms: Adonitol (Standard); Adonite (Standard)
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APOL1-IN-1 is an apolipoprotein L1 (APOL1) inhibitor that suppresses the functional activity of the APOL1 G1 risk variant. APOL1-IN-1 inhibits the pore function of APOL1, thereby reducing APOL1-mediated membrane permeability and abnormal ion flux, and thus intervenes in APOL1-related cellular injury processes. APOL1-IN-1 is used in research related to focal segmental glomerulosclerosis and non-diabetic kidney disease .
Synonyms: 2,3-DPG pentasodium salt
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2,3-Diphospho-D-glyceric acid (2,3-DPG) pentasodium salt is a hemoglobin binder and vascular calcification inhibitor that reduces the oxygen affinity of hemoglobin. 2,3-Diphospho-D-glyceric acid pentasodium salt also specifically delays the transformation of colloidal calciprotein particles into crystalline forms, thereby effectively inhibiting vascular smooth muscle cell calcification without affecting the normal formation of osteoid nodules in osteoblast-like cells. 2,3-Diphospho-D-glyceric acid pentasodium salt shows no cytotoxicity to tested cell lines and only weakly interferes with β-hematin formation mediated by glyceryl monopalmitate. 2,3-Diphospho-D-glyceric acid pentasodium salt can be used to study the pathological mechanisms of vascular calcification and malaria-related conditions .
Cat. No.: HY-100582S
Purity: 99.51%
Synonyms: Adonitol-1-13C; Adonite-1-13C
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Tri (2-methylphenyl) phosphine is a sterically hindered tertiary phosphine ligand. Tri (2-methylphenyl) phosphine forms a 1:1 crystalline adduct with copper (I) halides CuX (X = Cl, Br, I), yielding a centrosymmetric dinuclear copper (I) complex bridged by dihalides. Tri (2-methylphenyl) phosphine is applicable to coordination chemistry, synthesis of copper (I) halide complexes, and structural and spectral studies of phosphine-metal halide complexes .
Cat. No.: HY-W276164
CAS No.: 1120-04-3
Synonyms: Sodium stearyl sulfate
Cat. No.: HY-W127403
CAS No.: 19485-76-8
Synonyms: Cholesteryl trans-9-octadecenoate
Cat. No.: HY-W768324
Synonyms: Adonitol-13C5; Adonite-13C5
Cat. No.: HY-113278S
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Leucyl-phenylalanine- 13C6, 15N TFA is the 13C, 15N-labeled Leucyl-phenylalanine (HY-113278). Leucyl-phenylalanine is a linear dipeptide composed of L-leucine and L-phenylalanine, and also serves as a cyclization substrate. Leucyl-phenylalanine is an incomplete degradation product generated during protein breakdown or catabolism. Leucyl-phenylalanine undergoes heat-induced solid-state cyclization via an autocatalytic mechanism to form its cyclic diketopiperazine analog .
Cat. No.: HY-100582S1
Synonyms: Adonitol-2-13C; Adonite-2-13C
Cat. No.: HY-100582S2
Purity: 99.70%
Synonyms: Adonitol-3-13C; Adonite-3-13C
Cat. No.: HY-100582S3
Synonyms: Adonitol-5-13C; Adonite-5-13C
Cat. No.: HY-P10661
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
