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Cat. No.: HY-100582S3

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Ribitol-5-¹³C

(Synonyms: Adonitol-5-¹³C; Adonite-5-¹³C)

Ribitol-5-¹³C is the ¹³C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol

~~For research use only. We do not sell to patients.~~

Formula: C₄¹³CH₁₂O₅

Molecular Weight:153.14

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Ribitol-5-¹³C Chemical Structure

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Data Download

Data Sheet (267 KB)

Handling Instructions (2659 KB)

Other Forms of Ribitol-5-¹³C:

Ribitol
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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biological Activity

Description

Ribitol-5-¹³C is the ¹³C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol

All Endogenous Metabolite Isoforms :

Human Endogenous Metabolite

Microbial Metabolite

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 488-81-3

Molecular Weight 153.14

Formula C₄¹³CH₁₂O₅

SMILES

OC[C@@H]([C@@H]([C@@H]([13CH2]O)O)O)O

Synonyms

Adonitol-5-¹³C; Adonite-5-¹³C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Praissman JL, et al. The functional O-mannose glycan on α-dystroglycan contains a phospho-Ribitol primed for matriglycan addition. Elife. 2016 Apr 29;5. pii: e14473.;Toivari MH, et al. Enhancing the flux of D-glucose to the pentose phosphate pathway in Sa [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Ribitol-5-¹³C Related Classifications

HY-100582S3 Related Classifications

Others Metabolic Enzyme/Protease

Isotope-Labeled Compounds Endogenous Metabolite

Isotope-Labeled Compounds

Hot Research Area Internal Standard for Clinical Mass Spectrometry Internal Standard for Food Isotope-Labeled Inhibitors Isotope-Labeled Metabolites Carbon-13 (¹³C)

Stable Isotope-Labeled Inhibitors Stable isotope-labeled inhibitors for use in in vivo cell experiments Metabolic flux analysis: MFA Therapeutic Drug Monitoring: TDM

Others

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Keywords

Ribitol-5-¹³C
Adonitol-5-¹³C
Adonite-5-¹³C
Isotope-Labeled Compounds
Endogenous Metabolite
Inhibitor
inhibitor
inhibit

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Ribitol-5-13C

All Endogenous Metabolite Isoforms

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Help & FAQs

Ribitol-5-13C Related Classifications

HY-100582S3 Related Classifications

Ribitol-5-¹³C

Ribitol-5-¹³C Related Classifications