147 Results for "

cytotoxic T-lymphocyte

" in MedChemExpress (MCE) Product Catalog:
Products (147)

147 Results for "cytotoxic T-lymphocyte" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-P70527
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
HEK293
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6
6 Cited Publications
Cat. No.: HY-P7036
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Associated Antigen 8
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P9901
CAS No.: 477202-00-9
Synonyms: MDX-010; BMS-734016

Target:  

CTLA-4

Research Areas:  

Cancer

Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies .
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5
5 Cited Publications
Cat. No.: HY-P70753
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-P1569
CAS No.: 151705-84-9
Synonyms: LCMV GP(33-41) M-peptide; gp33 epitope
Target:  

Arenavirus

Research Areas:  

Infection Inflammation/Immunology

LCMV gp33-41, the carboxyl-extended 9-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
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4
4 Cited Publications
Cat. No.: HY-P1569A
Synonyms: LCMV GP(33-41) M-peptide TFA; gp33 epitope TFA
Target:  

Arenavirus

Research Areas:  

Inflammation/Immunology

LCMV gp33-41 (TFA), the carboxyl-extended 9-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
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3
3 Cited Publications
Cat. No.: HY-P79326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Rat
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-P700194AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-N0591
CAS No.: 477-43-0
Synonyms: (-)-Dehydrocostus lactone; Epiligulyl oxide
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) is a natural sesquiterpene that can be isolated from Saussurea lappa. Dehydrocostus Lactone has multiple activities such as anti-inflammatory, antibacterial, anti-tumor, and immunomodulatory effects. Dehydrocostus Lactone has an MIC of 2 µg/mL against Mycobacterium tuberculosis. Dehydrocostus Lactone can also inhibit the killing activity of cytotoxic T lymphocytes and induce apoptosis in tumor cells .
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2
2 Cited Publications
Cat. No.: HY-P99762
CAS No.: 2069959-72-2
Synonyms: MGD009

Target:  

CD3

Research Areas:  

Cancer

Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer .
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2
2 Cited Publications
Cat. No.: HY-P76377
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GZMA; cytotoxic T-lymphocyte Proteinase 1; Prev. CTLA3; Granzyme 1; Prev. HFSP; H Factor; CTL Tryptase; HF; Fragmentin-1; Granzyme A (cytotoxic T-lymphocyte-Associated Serine Esterase-3; Hanukah Factor Serine Protease); Granzyme A (Granzyme 1, cytotoxic T
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P7372
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P7373
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P81114
Synonyms: Interleukin-17A; CTLA-8; CTLA 8; CTLA8; cytotoxic T lymphocyte associated antigen 8; cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL-17A; IL-17; Interleukin 17; Interleukin-17; Interleukin 17A; Interleukin17; Interleukin17A; IL17_HUMAN; IL17_MOUSE.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-160768
Target:  

Deubiquitinase

Research Areas:  

Inflammation/Immunology Cancer

OTUB2-IN-1, a specific inhibitor of OTUB2 (KD: ~12 μM), reduces PD-L1 protein expression in tumor cells and inhibits tumor growth by promoting robust intra-tumor infiltration of cytotoxic T lymphocytes (CTL) .
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1
1 Cited Publications
Cat. No.: HY-P73171
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P73175
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Rabbit
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P78556
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; cytotoxic T-lymphocyte-Assoc
Species:  
Rat
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-N3005
CAS No.: 33627-28-0
Britannin is an NLRP3 inhibitor with an IC50 of 3.630 μM, exhibiting anti-inflammatory activity. Britannin inhibits the activation and assembly of the NLRP3 inflammasome by blocking the interaction between NLRP3 and NEK7. Additionally, Britannin demonstrates antitumor activity by inhibiting the proliferation of tumor cells through blocking the interaction between HIF-1α and Myc, thereby suppressing PD-L1 expression and enhancing cytotoxic T lymphocyte activity. Britannin can also induce apoptosis and autophagy in liver cancer cells by activating ROS-regulated AMPK. Britannin holds promise for research in the fields of anti-inflammatory and antitumor therapeutics .
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1
1 Cited Publications
Cat. No.: HY-P99144A

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse PD-1 Antibody (S-5001) is a selective inhibitor targeting PD-1, blocking the PD-1/PD-L1 immune checkpoint axis through competitive binding to PD-1. Anti-Mouse PD-1 Antibody (S-5001) works by reversing the tumor immunosuppressive microenvironment and reactivating the anti-tumor activity of cytotoxic T lymphocytes. It can be used in research on tumors such as melanoma and HPV-positive oropharyngeal squamous cell carcinoma. Anti-Mouse PD-1 Antibody (S-5001) is often combined with photothermal therapy, chemotherapy, etc., to enhance efficacy .
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